⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178083 | 1.00 | — | — | |
| SCHEMBL9341838 | 0.84 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL20494918 | 0.79 | TDP1 (0.40) | — | |
| SCHEMBL26604318 | 0.78 | PARP10 (0.53) | — | |
| SCHEMBL8461932 | 0.75 | TSHR (0.63) | — | |
| Benzophenone SCHEMBL27820353 | 0.75 | ALDH1A1 (0.74) | — | |
| SCHEMBL3929950 | 0.73 | CES1 (0.47) | — | |
| SCHEMBL525632 | 0.73 | — | — | |
| SCHEMBL2234110 | 0.73 | CES1 (0.47) | — | |
| SCHEMBL188438 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759543-B1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-9487693-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| EP-2725017-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2016-06-29 | — | — | EP | disclosed |
| EP-2669277-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2015-07-01 | — | — | EP | disclosed |
| EP-2684886-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2015-06-03 | — | — | EP | disclosed |
| EP-2669278-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2015-05-27 | — | — | EP | disclosed |
| US-8916071-B2 | Chromene compound and curable composition | TOKUYAMA CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| EP-2554624-B1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-20140225050-A1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2014-08-14 | — | — | US | disclosed |
| EP-2759543-A1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | Tokuyama Corporation (JP) | 2014-07-30 | — | — | EP | disclosed |
| EP-1655293-A2 | Chromene compound | Tokuyama Corporation (JP) | 2006-05-10 | — | — | EP | disclosed |
| US-6723859-B2 | BASE STRUCTURE IS A CHROMENE(3,2-A)FLUORENE RING CONTAINING SPIRO-FUSED RINGS; PHOTOCHROMIC LENSES; LARGE FADING RATE, LESS COLOR WHEN DETERIORATED, AND EXCELLENT LIGHT RESISTANCE IN THE PHOTOCHROMIC PROPERTIES | TOKUYAMA CORPORATION (JP) | 2004-04-20 | — | — | US | disclosed |
| US-20040014995-A1 | Chromene compounds | KAWABATA YUICHIRO (JP) | 2004-01-22 | — | — | US | disclosed |
| US-20030096117-A1 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2003-05-22 | — | — | US | disclosed |
| US-6469076-B1 | Chromene compounds | TOKUYAMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1054010-B1 | Chromene compound | TOKUYAMA CORP (JP) | 2002-07-24 | — | — | EP | disclosed |
| EP-1184379-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-6340765-B1 | PHOTOCHROMIC DYES AND DEVELOPMENT | TOKUYAMA CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1116723-A1 | CHROMENE COMPOUNDS | TOKUYAMA CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| EP-1054010-A1 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2000-11-22 | — | — | EP | disclosed |