SCHEMBL29065729

SCHEMBL29065729

CC(c1ccc(F)cc1)[Si](C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.39
TDO2 P48775 2/20 0.39
CYP17A1 P05093 1/20 0.38
ACHE P22303 1/20 0.38
AOC3 Q16853 2/20 0.35
CYP19A1 P11511 1/20 0.35
DAO P14920 1/20 0.35
HTT P42858 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15952487 0.87 ESR1 (0.41) HTTTRPA1
SCHEMBL23255883 0.77 ESR1 (0.59) NPC1RAB9A
SCHEMBL19019727 0.76 IDO1 (0.42) IDO1TDO2CYP17A1ACHEAOC3
SCHEMBL9854662 0.75 CYP2A6 (0.40) CYP19A1
SCHEMBL6420857 0.74 TAAR1 (0.42) TRPA1
SCHEMBL12027408 0.73 IDO1 (0.46) IDO1TDO2ACHEAOC3DAO
SCHEMBL84956 0.73 IDO1 (0.46) IDO1TDO2ACHEAOC3DAO
SCHEMBL7893366 0.73 ESR1 (0.52) IDO1TDO2CYP17A1ACHEAOC3
Ammonia Solution, Strong SCHEMBL7995946 0.70 ESR1 (0.50) IDO1TDO2CYP17A1ACHEAOC3
SCHEMBL21840890 0.70 IDO1 (0.44) IDO1TDO2CYP17A1ACHEAOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444483-A Preparation method of 1,3-dithiane substituted diene derivative 兰州大学 2023-07-18 CN disclosed