SCHEMBL19019727

SCHEMBL19019727

CC(c1ccc(F)cc1)[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.42
TDO2 P48775 2/20 0.42
CYP17A1 P05093 1/20 0.33
AOC3 Q16853 2/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ACHE P22303 1/20 0.31
DAO P14920 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19019729 0.80 ADRB2 (0.43) IDO1TDO2SLC6A4
SCHEMBL9153510 0.80 ALOX5 (0.33) SLC6A2SLC6A4SLC6A3HTT
SCHEMBL17520022 0.79 TAAR1 (0.35) IDO1TDO2
SCHEMBL19019754 0.78 CA1 (0.42) CYP17A1ACHEHTT
SCHEMBL19019720 0.77 LMNA (0.39)
SCHEMBL29065729 0.76 IDO1 (0.39) IDO1TDO2CYP17A1AOC3ACHE
SCHEMBL14522308 0.72 ESR1 (0.52) SLC6A2SLC6A3
SCHEMBL7063054 0.71 TAAR1 (0.32) IDO1TDO2
SCHEMBL26249056 0.69 CA1 (0.46) CYP17A1ACHEHTT
SCHEMBL84956 0.65 IDO1 (0.46) IDO1TDO2AOC3ACHEDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3184172-B1 HYDROSILYLATION IRON CATALYST UNIV KYUSHU NAT UNIV CORP (JP) 2024-09-04 EP disclosed
CN-106573235-B Iron hydrosilylate catalyst 国立大学法人九州大学 2020-07-07 CN disclosed
US-10239896-B2 Hydrosilylation iron catalyst KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2019-03-26 US disclosed
US-20170260216-A1 HYDROSILYLATION IRON CATALYST KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-09-14 US disclosed
EP-3184172-A1 HYDROSILYLATION IRON CATALYST Kyushu University, National University Corporation (JP) 2017-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10239896-B2 Hydrosilylation iron catalyst SLC40A1, FTH1, SFXN1 IDO1 255/4885TDO2 207/4885CYP17A1 1718/4885
US-20170260216-A1 HYDROSILYLATION IRON CATALYST SLC40A1, FTH1, SFXN1 IDO1 255/4885TDO2 207/4885CYP17A1 1718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.