SCHEMBL29065862

SCHEMBL29065862

Cc1ccc(NC(c2ccccc2[N+](=O)[O-])C2CCCCC2=O)cc1

nearest known ligand 0.83

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 0.83
MAPT P10636 4/20 0.50
LMNA P02545 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
KDM4E B2RXH2 1/20 0.50
HPGD P15428 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 4/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CA12 O43570 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29065866 0.91 CA1 (1.00) CA1MAPTLMNANPSR1KDM4E
SCHEMBL29065864 0.83 CA1 (0.61) CA1MAPTLMNAKDM4EHPGD
SCHEMBL29065877 0.82 MAPT (0.60) CA1MAPTLMNANPSR1KDM4E
SCHEMBL29065870 0.81 CA1 (0.55) CA1MAPTLMNANPSR1KDM4E
SCHEMBL29065875 0.79 CA1 (0.82) CA1MAPTLMNANPSR1KDM4E
SCHEMBL28015291 0.77 CA1 (0.82) CA1MAPTLMNANPSR1KDM4E
SCHEMBL3486370 0.75 CA1 (0.65) CA1MAPTALDH1A1MEN1KMT2A
SCHEMBL30960322 0.75 CA1 (0.65) CA1MAPTALDH1A1MEN1KMT2A
SCHEMBL13254535 0.75 CA1 (0.65) CA1MAPTALDH1A1MEN1KMT2A
SCHEMBL29065865 0.73 CA1 (0.76) CA1MAPTLMNANPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715596-B Method for synthesizing beta-aminoketone compound by synergistic catalysis of cyclopentadienyl titanium/Bronsted acid 宁夏师范学院 2025-01-14 CN disclosed
CN-116715596-A Method for synthesizing beta-aminoketone compound by synergistic catalysis of cyclopentadienyl titanium/Bronsted acid 宁夏师范学院 2023-09-08 CN disclosed