SCHEMBL29065869

SCHEMBL29065869

C=CC(=O)OC(C)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28552992 0.95 TSHR (0.34) TSHRKDM4ETDP1GAA
SCHEMBL1263586 0.86 TSHR (0.37) TSHR
SCHEMBL646641 0.84 TSHR (0.36) TSHR
SCHEMBL14312167 0.83 TSHR (0.35) TSHR
SCHEMBL5087397 0.83 TSHR (0.35) TSHR
SCHEMBL2141800 0.83 TSHR (0.35) TSHR
SCHEMBL223954 0.83 TSHR (0.35) TSHR
SCHEMBL7899865 0.83 TSHR (0.35) TSHR
SCHEMBL4893018 0.83 TSHR (0.35) TSHR
SCHEMBL347671 0.83 TSHR (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116712757-A Organic silicon composition and preparation method thereof 江苏四新科技应用研究所股份有限公司 2023-09-08 CN disclosed