Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21360450 | 0.87 | ATM (0.43) | ATMPARP1DDB1CRBNALDH1A1 | |
| SCHEMBL19390116 | 0.87 | ATM (0.41) | ATMPARP1DDB1CRBNALDH1A1 | |
| SCHEMBL3941124 | 0.87 | ATM (0.43) | ATMPARP1DDB1CRBNALDH1A1 | |
| SCHEMBL19097297 | 0.84 | ATM (0.52) | ATMPARP1DDB1CRBNALDH1A1 | |
| SCHEMBL580926 | 0.83 | ATM (0.39) | ATMPARP1DDB1CRBNALDH1A1 | |
| SCHEMBL10323559 | 0.82 | PARP1 (0.38) | ATMPARP1DDB1CRBNKDM1A | |
| SCHEMBL642245 | 0.82 | ATM (0.45) | ATMPARP1DDB1CRBNALDH1A1 | |
| SCHEMBL30077839 | 0.82 | ATM (0.38) | ATMPARP1DDB1CRBNALDH1A1 | |
| SCHEMBL8263573 | 0.82 | ATM (0.38) | ATMPARP1DDB1CRBNALDH1A1 | |
| SCHEMBL9965481 | 0.82 | ATM (0.45) | ATMPARP1DDB1CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715671-A | Application of alpha-chromene spiropiperidine compound in preparation of 5-hydroxytryptamine 2C receptor agonist | 苏州大学 | 2023-09-08 | — | — | CN | disclosed |