Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642245 | 1.00 | ATM (0.45) | ATMALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL19097297 | 0.92 | ATM (0.52) | ATMALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL21360450 | 0.86 | ATM (0.43) | ATMALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3941124 | 0.86 | ATM (0.43) | ATMALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL5137199 | 0.84 | SMN1; SMN2 (0.40) | ATMALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL19390116 | 0.83 | ATM (0.41) | ATMALDH1A1KMT2AMEN1PARP1 | |
| SCHEMBL29065904 | 0.82 | ATM (0.40) | ATMALDH1A1PARP1DDB1CRBN | |
| SCHEMBL3635011 | 0.81 | OPRK1 (0.33) | ELANE | |
| SCHEMBL10174353 | 0.81 | ELANE (0.39) | KMT2AMEN1ELANE | |
| SCHEMBL9965482 | 0.81 | ELANE (0.39) | KMT2AMEN1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960347-B1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | STERIX LTD (GB) | 2012-06-20 | — | — | EP | disclosed |