SCHEMBL29066089

SCHEMBL29066089

COc1ccc(CCC(=O)c2cc(OC)c(OC)c(OC)c2)cc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 7/20 0.67
TUBB4A P04350 6/20 0.67
TUBB P07437 6/20 0.67
TUBA3C P0DPH7 6/20 0.67
TUBA1B P68363 6/20 0.67
TUBA4A P68366 6/20 0.67
TUBB4B P68371 6/20 0.67
TUBB3 Q13509 6/20 0.67
TUBB2A Q13885 6/20 0.67
TUBB8 Q3ZCM7 6/20 0.67
TUBA3E Q6PEY2 6/20 0.67
TUBA1A Q71U36 6/20 0.67
TUBA1C Q9BQE3 6/20 0.67
TUBB6 Q9BUF5 6/20 0.67
TUBB2B Q9BVA1 6/20 0.67
CYP19A1 P11511 1/20 0.65
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
TSHR P16473 1/20 0.54
NFKB1 P19838 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30504067 1.00 TUBB1 (0.67) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL7197444 0.86 TUBB1 (0.62) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL29066087 0.86 TUBB1 (0.67) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL30504084 0.86 TUBB1 (0.67) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL31275137 0.84 CYP19A1 (0.74) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL17536647 0.84 CYP19A1 (0.74) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL17536646 0.81 CYP19A1 (0.74) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL1535646 0.81 TUBB4A (1.00) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL29349837 0.81 TUBB4A (1.00) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL30834904 0.80 CYP19A1 (0.61) TUBB1TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535304-A Erianin analogue, and synthetic method and application thereof 中国科学院成都生物研究所 2023-08-04 CN disclosed