Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102987 | 1.00 | CTSK (0.46) | CTSKBTKUSP2SMN1; SMN2GAA | |
| SCHEMBL28851225 | 1.00 | CTSK (0.46) | CTSKBTKUSP2SMN1; SMN2GAA | |
| SCHEMBL29629085 | 0.90 | BTK (0.49) | CTSKBTKUSP2SMN1; SMN2GAA | |
| SCHEMBL1957109 | 0.88 | CTSK (0.47) | CTSKBTKUSP2SMN1; SMN2GAA | |
| SCHEMBL1699991 | 0.88 | CTSK (0.47) | CTSKBTKUSP2SMN1; SMN2GAA | |
| SCHEMBL880564 | 0.88 | CTSK (0.47) | CTSKBTKUSP2SMN1; SMN2GAA | |
| SCHEMBL21166305 | 0.86 | GAA (0.42) | CTSKBTKUSP2SMN1; SMN2GAA | |
| SCHEMBL12714581 | 0.86 | BTK (0.53) | CTSKBTKGAAKMT2AL3MBTL1 | |
| SCHEMBL31327089 | 0.84 | CTSK (0.51) | CTSKBTKGAAKMT2AL3MBTL1 | |
| SCHEMBL13497425 | 0.83 | CTSK (0.47) | CTSKBTKGAAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109032-B | Quinoline derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-09-05 | — | — | CN | disclosed |