SCHEMBL2906650

SCHEMBL2906650

NC(=O)C(CC=NO)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.54
CYP2C19 P33261 3/20 0.46
CYP2D6 P10635 2/20 0.39
CYP1A2 P05177 1/20 0.39
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
LMNA P02545 3/20 0.38
MAPK1 P28482 2/20 0.38
SLC6A3 Q01959 3/20 0.38
DRD3 P35462 2/20 0.38
ADORA3 P0DMS8 1/20 0.38
EDNRB P24530 1/20 0.38
MC4R P32245 1/20 0.38
MC3R P41968 1/20 0.38
DRD2 P14416 1/20 0.38
BCAT2 O15382 1/20 0.38
GABBR2 O75899 1/20 0.36
GABBR1 Q9UBS5 1/20 0.36
SRC P12931 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6711147 0.80 EPHX1 (0.59) EPHX1CYP2C19CYP2D6CYP1A2PKM
SCHEMBL6160071 0.79 KMT2A (0.50) CYP2C19LMNASLC6A3
SCHEMBL6160065 0.79 KMT2A (0.50) CYP2C19LMNASLC6A3
SCHEMBL28223386 0.79 EPHX1 (0.58) EPHX1CYP2C19CYP2D6CYP1A2PKM
SCHEMBL6631805 0.79 CYP2C19 (0.73) EPHX1CYP2C19CYP2D6CYP1A2PKM
SCHEMBL8620344 0.77 CYP2C19 (0.71) EPHX1CYP2C19CYP2D6CYP1A2PKM
SCHEMBL8624668 0.77 CYP2C19 (0.71) EPHX1CYP2C19CYP2D6CYP1A2PKM
SCHEMBL22758081 0.76 EPHX1 (0.54) EPHX1CYP2C19CYP2D6CYP1A2PKM
SCHEMBL22758080 0.76 EPHX1 (0.54) EPHX1CYP2C19CYP2D6CYP1A2PKM
SCHEMBL27608796 0.75 HTR2A (0.41) CYP2C19CYP2D6LMNAMAPK1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2223969-B1 RESIN COMPOSITION, TRANSPARENT MEMBER OBTAINED FROM THE RESIN COMPOSITION, AND USE OF THE SAME MITSUI CHEMICALS INC (JP) 2015-02-25 EP disclosed
US-8648130-B2 Resin composition, transparent member obtained from the resin composition, and use of the same MITSUI CHEMICALS, INC. (JP) 2014-02-11 US disclosed
CN-101883825-B Resin composition, transparent member obtained from the resin composition, and use of the same MITSUI CHEMICALS INC 2013-11-06 CN disclosed
CN-101883825-A Resin composition, transparent member obtained from the resin composition, and use of the same MITSUI CHEMICALS INC 2010-11-10 CN disclosed
US-20100256271-A1 RESIN COMPOSITION, TRANSPARENT MEMBER OBTAINED FROM THE RESIN COMPOSITION, AND USE OF THE SAME MITSUI CHEMICALS, INC. (JP) 2010-10-07 US disclosed
EP-2223969-A1 RESIN COMPOSITION, TRANSPARENT MEMBER OBTAINED FROM THE RESIN COMPOSITION, AND USE OF THE SAME Mitsui Chemicals, Inc. (JP) 2010-09-01 EP disclosed