Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27757333 | 0.80 | LMNA (0.51) | CYP2C19LMNAKDM4EL3MBTL1 | |
| SCHEMBL9803628 | 0.78 | LMNA (0.44) | TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL9803625 | 0.78 | LMNA (0.44) | TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL27460482 | 0.76 | HTR2A (0.39) | HTR2ATAAR1CYP2C19HRH1KDM4E | |
| SCHEMBL2906650 | 0.75 | EPHX1 (0.54) | CYP2C19LMNAMAPK1CYP2D6SRC | |
| SCHEMBL29211922 | 0.73 | GSR (0.35) | CYP2C19LMNAMAPK1CYP2D6 | |
| SCHEMBL29211923 | 0.72 | GSR (0.34) | CYP2C19LMNAMAPK1 | |
| SCHEMBL30481449 | 0.72 | ACP3 (0.42) | SRCCA2 | |
| SCHEMBL6160071 | 0.72 | KMT2A (0.50) | CYP2C19LMNA | |
| SCHEMBL6160065 | 0.72 | KMT2A (0.50) | CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100357282-C | Isothiazole derivatives, process for the preparation thereof, and pharmaceutical composition including the same | CJ CORP (KR) | 2007-12-26 | — | — | CN | disclosed |
| CN-1705650-A | Isothiazole derivatives, process for preparing the same, and pharmaceutical composition comprising the same | CJ CORP (KR) | 2005-12-07 | — | — | CN | disclosed |