Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | CTSB | P07858 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29066538 | 0.91 | KDM4E (0.67) | KDM4EJMJD7MAPTALDH1A1L3MBTL1 | |
| SCHEMBL23698707 | 0.85 | KDM4E (0.65) | KDM4EJMJD7MAPTALDH1A1L3MBTL1 | |
| SCHEMBL28433932 | 0.84 | JMJD7 (0.57) | KDM4EJMJD7MAPTALDH1A1L3MBTL1 | |
| SCHEMBL29066537 | 0.83 | JMJD7 (0.56) | KDM4EJMJD7MAPTALDH1A1L3MBTL1 | |
| SCHEMBL29066526 | 0.83 | KDM4E (0.54) | KDM4EJMJD7MAPTALDH1A1L3MBTL1 | |
| SCHEMBL30421287 | 0.81 | JMJD7 (0.53) | KDM4EJMJD7MAPTALDH1A1L3MBTL1 | |
| SCHEMBL21816873 | 0.81 | JMJD7 (0.53) | KDM4EJMJD7MAPTALDH1A1L3MBTL1 | |
| SCHEMBL28423498 | 0.81 | JMJD7 (0.54) | KDM4EJMJD7MAPTALDH1A1L3MBTL1 | |
| SCHEMBL29066528 | 0.81 | JMJD7 (0.48) | KDM4EJMJD7MAPTALDH1A1L3MBTL1 | |
| SCHEMBL23698662 | 0.81 | JMJD7 (0.52) | KDM4EJMJD7MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283764-A | Nitroquinoline prodrug, preparation method and application thereof | 江苏亚虹医药科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116283763-A | Nitroquinoline prodrug, preparation method and application thereof | 江苏亚虹医药科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |