Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD7 | P0C870 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29066525 | 0.91 | JMJD7 (0.49) | JMJD7MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29066517 | 0.91 | JMJD7 (0.49) | JMJD7MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL21816873 | 0.90 | JMJD7 (0.53) | JMJD7MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL30421287 | 0.90 | JMJD7 (0.53) | JMJD7MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29066512 | 0.90 | JMJD7 (0.48) | JMJD7MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29066528 | 0.89 | JMJD7 (0.48) | JMJD7MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29066542 | 0.88 | JMJD7 (0.47) | JMJD7MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29066536 | 0.86 | JMJD7 (0.48) | JMJD7MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL30421570 | 0.86 | JMJD7 (0.48) | JMJD7MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL23698707 | 0.85 | KDM4E (0.65) | JMJD7MAPTKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12152048-B2 | Nitroxoline prodrug and use thereof | JIANGSU YAHONG MEDITECH CO., LTD. (CN) | 2024-11-26 | — | — | US | disclosed |
| US-20210363165-A1 | NITROXOLINE PRODRUG AND USE THEREOF | JIANGSU YAHONG MEDITECH CO., LTD. (CN) | 2021-11-25 | — | — | US | disclosed |
| US-20210363165-A1 | NITROXOLINE PRODRUG AND USE THEREOF | JIANGSU YAHONG MEDITECH CO., LTD. (CN) | 2021-11-25 | — | — | US | disclosed |
| EP-3858814-A1 | NITROXOLINE PRODRUG AND USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858814-A1 | NITROXOLINE PRODRUG AND USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12152048-B2 | Nitroxoline prodrug and use thereof | NOS1, NOS2, NNT | JMJD7 2021/4885MAPT 2243/4885KDM4E 2742/4885 |
| US-20210363165-A1 | NITROXOLINE PRODRUG AND USE THEREOF | NOS1, NOS2, NNT | JMJD7 2021/4885MAPT 2243/4885KDM4E 2742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.