Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.35 |
| ▸ | PLAT | P00750 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29066865 | 1.00 | CDK2 (0.45) | CDK2KDM4EALDH1A1GLAHPGD | |
| SCHEMBL15288383 | 0.68 | CDK2 (0.61) | CDK2KDM4EALDH1A1GLAHPGD | |
| SCHEMBL15288758 | 0.67 | CDK2 (0.64) | CDK2CSNK2A1BCL6 | |
| SCHEMBL30524307 | 0.67 | CDK2 (0.54) | CDK2CSNK2A1GSK3BBCL6 | |
| SCHEMBL19753996 | 0.66 | CDK2 (0.50) | CDK2KDM4EALDH1A1GLAHPGD | |
| SCHEMBL21067605 | 0.62 | CDK2 (1.00) | CDK2KDM4EALDH1A1GLAHPGD | |
| SCHEMBL19742650 | 0.62 | CDK2 (0.45) | CDK2KDM4EALDH1A1GLAHPGD | |
| SCHEMBL19742653 | 0.61 | CDK2 (0.46) | CDK2CSNK2A1GSK3BBCL6 | |
| SCHEMBL18343698 | 0.60 | KDM4E (0.59) | CDK2KDM4EALDH1A1GLAHPGD | |
| SCHEMBL8226808 | 0.60 | KDM4E (0.49) | CDK2KDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693538-A | Pyrazolopyrimidine derivative, and preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2023-09-05 | — | — | CN | disclosed |