Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | BCL6 | P41182 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 8/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.40 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | HIPK3 | Q9H422 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15288758 | 0.82 | CDK2 (0.64) | CDK2CSNK2A1KCNH2BCL6CSNK2A2 | |
| SCHEMBL21067605 | 0.70 | CDK2 (1.00) | CDK2CSNK2A1BCL6CSNK2A2 | |
| SCHEMBL29066866 | 0.68 | CDK2 (0.48) | CDK2CSNK2A1KCNH2BCL6CSNK2A2 | |
| SCHEMBL29066870 | 0.68 | CDK2 (0.48) | CDK2CSNK2A1KCNH2BCL6CSNK2A2 | |
| SCHEMBL25593647 | 0.67 | CDK2 (0.42) | CDK2CSNK2A1CSNK2A2GSK3BHIPK2 | |
| SCHEMBL29066865 | 0.67 | CDK2 (0.45) | CDK2CSNK2A1BCL6GSK3B | |
| SCHEMBL29066869 | 0.67 | CDK2 (0.45) | CDK2CSNK2A1BCL6GSK3B | |
| SCHEMBL15288383 | 0.66 | CDK2 (0.61) | CDK2CSNK2A1 | |
| SCHEMBL19753996 | 0.65 | CDK2 (0.50) | CDK2CSNK2A1BCL6CSNK2A2 | |
| SCHEMBL22413306 | 0.65 | CDK2 (0.59) | CDK2CSNK2A1CSNK2A2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693538-A | Pyrazolopyrimidine derivative, and preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2023-09-05 | — | — | CN | disclosed |