SCHEMBL29067010

SCHEMBL29067010

CCO[Si](C)(OC)OC(=O)CC(C)=O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.46
GAA P10253 2/20 0.46
SI P14410 2/20 0.46
MGAM2 Q2M2H8 2/20 0.46
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29067011 0.88 MGAM (0.59) MGAMGAASIMGAM2TSHR
SCHEMBL16616580 0.82 ALDH1A1 (0.37) MGAMGAASIMGAM2TSHR
SCHEMBL29067009 0.78 MGAM (0.43) MGAMGAASIMGAM2
SCHEMBL5068478 0.78 MGAM (0.46) MGAMGAASIMGAM2
SCHEMBL27550157 0.77 ALDH1A1 (0.41) TSHR
SCHEMBL3919518 0.74 MGAM (0.40) MGAMGAASIMGAM2TSHR
SCHEMBL15164021 0.74 MGAM (0.38) MGAMGAASIMGAM2TSHR
SCHEMBL29067008 0.74 MGAM (0.43) MGAMGAASIMGAM2
SCHEMBL28049534 0.74 CYP1A2 (0.33) MGAMGAASIMGAM2
SCHEMBL7071406 0.73 MGAM (0.39) MGAMGAASIMGAM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901725-B Polydiorganosiloxane preparation 美国陶氏有机硅公司 2023-09-08 CN disclosed