Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 10/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21378529 | 0.99 | PHGDH (0.46) | PHGDHMAPTALDH1A1NPSR1ACACB | |
| SCHEMBL21378527 | 0.99 | PHGDH (0.46) | PHGDHMAPTALDH1A1NPSR1ACACB | |
| SCHEMBL21378568 | 0.90 | HDAC3 (0.43) | MAPTALDH1A1NPSR1ACACBKMT2A | |
| SCHEMBL21378571 | 0.90 | HDAC3 (0.43) | MAPTALDH1A1NPSR1ACACBKMT2A | |
| SCHEMBL21378587 | 0.90 | LMNA (0.48) | MAPTALDH1A1ACACBHIF1AKMT2A | |
| SCHEMBL21378590 | 0.90 | LMNA (0.48) | MAPTALDH1A1ACACBHIF1AKMT2A | |
| SCHEMBL17966968 | 0.90 | LMNA (0.48) | MAPTALDH1A1ACACBHIF1AKMT2A | |
| SCHEMBL18551119 | 0.88 | ACACB (0.42) | MAPTALDH1A1ACACBKMT2AMEN1 | |
| SCHEMBL18611922 | 0.88 | ACACB (0.42) | ALDH1A1ACACBCTSKUSP2HSD17B10 | |
| SCHEMBL21388688 | 0.81 | ACACB (0.47) | MAPTACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507607-A | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2023-07-28 | — | — | CN | disclosed |