SCHEMBL29067372

SCHEMBL29067372

COC(=O)C1(C(C)N)CC1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.42
LMNA P02545 1/20 0.33
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29067374 1.00 NPSR1 (0.42) NPSR1LMNACYP4F2CYP4A11CYP1A2
SCHEMBL29067370 1.00 NPSR1 (0.42) NPSR1LMNACYP4F2CYP4A11CYP1A2
SCHEMBL5515153 0.81 NPSR1 (0.40) NPSR1LMNACYP4F2CYP4A11CYP1A2
SCHEMBL16104372 0.78 NPSR1 (0.41) NPSR1LMNACYP4F2CYP4A11
SCHEMBL27640880 0.77 NPSR1 (0.38) NPSR1LMNACYP4F2CYP4A11CYP1A2
SCHEMBL29067373 0.77 ALOX15 (0.38) LMNACYP2C9
SCHEMBL29067375 0.77 ALOX15 (0.38) LMNACYP2C9
SCHEMBL18418871 0.74 NPSR1 (0.39) NPSR1LMNACYP4F2CYP4A11
SCHEMBL669743 0.73
SCHEMBL5515078 0.73 NPSR1 (0.47) NPSR1LMNACYP4F2CYP4A11CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730849-A Preparation method of optically active [1- (1-amino ethyl) cyclopropyl ] methanol 江苏艾迪药业股份有限公司 2023-09-12 CN disclosed