Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27697845 | 0.91 | PNMT (0.54) | PNMTDRD2DRD4DRD3MMP12 | |
| SCHEMBL8151881 | 0.90 | PNMT (0.64) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL28781055 | 0.84 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 | |
| Alcohol SCHEMBL16265499 | 0.83 | PNMT (0.55) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7195192 | 0.83 | PNMT (0.72) | PNMTDRD2DRD4DRD3KDR | |
| SCHEMBL7607164 | 0.81 | PNMT (0.70) | PNMTDRD2DRD4DRD3KDR | |
| SCHEMBL7606240 | 0.81 | PNMT (0.70) | PNMTDRD2DRD4DRD3KDR | |
| SCHEMBL28562503 | 0.81 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL6742021 | 0.81 | PNMT (0.53) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL28054695 | 0.81 | PNMT (0.53) | PNMTDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730787-A | Preparation method of 9, 9-dibenzyl-9-hydrogen-fluorene | 广西中烟工业有限责任公司 | 2023-09-12 | — | — | CN | disclosed |