Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43895 | 0.94 | SPHK2 (0.36) | SPHK2SPHK1TSHRALDH1A1LMNA | |
| SCHEMBL44286 | 0.94 | SPHK2 (0.36) | SPHK2SPHK1TSHRALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL351073 | 0.92 | SPHK2 (0.35) | SPHK2SPHK1TSHRALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL3613960 | 0.92 | SPHK2 (0.35) | SPHK2SPHK1TSHRALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL988664 | 0.92 | SPHK2 (0.35) | SPHK2SPHK1TSHRALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL164104 | 0.92 | SPHK2 (0.35) | SPHK2SPHK1TSHRALDH1A1LMNA | |
| SCHEMBL44180 | 0.91 | TSHR (0.36) | SPHK2SPHK1TSHRALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL120845 | 0.88 | TSHR (0.35) | SPHK2SPHK1TSHRRECQL | |
| Hydrochloric Acid SCHEMBL432534 | 0.88 | TSHR (0.35) | SPHK2SPHK1TSHRRECQL | |
| SCHEMBL14601136 | 0.84 | SPHK2 (0.31) | SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116732024-A | Functional modified magnetic bead, DNA gel recovery kit and preparation method and application thereof | 广州飞扬生物工程有限公司 | 2023-09-12 | — | — | CN | disclosed |