Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SOD1 | P00441 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloromethane SCHEMBL15655633 | 0.83 | MIF (0.43) | MIFGRIN2B | |
| SCHEMBL2489084 | 0.83 | MIF (0.71) | MIFGRIN2B | |
| SCHEMBL8816811 | 0.82 | GABRA1 (0.37) | MIFCYP2C19RXRARXRB | |
| SCHEMBL460071 | 0.82 | POLB (0.34) | MIFACHEBCHECYP2C19RXRA | |
| SCHEMBL5465655 | 0.81 | MIF (0.47) | MIFCYP1A2CYP2C19GRIN2B | |
| SCHEMBL26785 | 0.81 | MIF (0.47) | MIFCYP1A2CYP2C19GRIN2B | |
| SCHEMBL1457268 | 0.80 | GABRA1 (0.41) | MIFCYP1A2SOD1KIF11GRIN2B | |
| SCHEMBL30317997 | 0.80 | GABRA1 (0.41) | MIFCYP1A2SOD1KIF11GRIN2B | |
| SCHEMBL22471928 | 0.79 | MIF (0.46) | MIFCYP1A2CYP2C19GRIN2B | |
| SCHEMBL28048374 | 0.79 | MIF (0.46) | MIFCYP1A2CYP2C19GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116533420-A | Preparation method of near infrared barrier polyurethane lens | 浙江伟星光学股份有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-112391048-A | Polyurethane lens with infrared and blue light prevention function and manufacturing method thereof | 上海伟星光学有限公司 | 2021-02-23 | — | — | CN | claimed |
| CN-117321140-A | Aging-resistant moisture-curable composition | 科思创德国股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117203252-A | Process for preparing isocyanate group-terminated polyoxazolidone compositions | 科思创德国股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116568719-A | Compositions comprising epoxy-functional oxazolidinones | 科思创德国股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-116533420-A | Preparation method of near infrared barrier polyurethane lens | 浙江伟星光学股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116486694-A | Display protector | 白石有限公司 | 2023-07-25 | — | — | CN | disclosed |
| EP-4157912-A1 | COMPOSITIONS CONTAINING URETDIONE GROUPS CROSSLINKING AT LOW TEMPERATURES | Covestro Deutschland AG (DE) | 2023-04-05 | — | — | EP | disclosed |
| CN-115605525-A | Uretdione group-containing compositions which crosslink at low temperatures | 科思创德国股份有限公司（DE） | 2023-01-13 | — | — | CN | disclosed |
| EP-4107198-A1 | POLYISOCYANATE PREPARATIONS | Covestro Deutschland AG (DE) | 2022-12-28 | — | — | EP | disclosed |
| CN-115464965-A | Display protector | 白石有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-113238304-A | Method for manufacturing zirconium dioxide-loaded antibacterial polyurethane lens by adopting coated silver ions | 上海伟星光学有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-109476812-B | Low hardness polyurethane dispersions | 科思创德国股份有限公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-112566957-A | Ionically hydrophilicized polyisocyanates having improved drying properties | 科思创知识产权两合公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112391048-A | Polyurethane lens with infrared and blue light prevention function and manufacturing method thereof | 上海伟星光学有限公司 | 2021-02-23 | — | — | CN | disclosed |
| WO-2021004980-A1 | PROCESS OF PREPARING ALLOPHANATE- AND/OR THIOALLOPHANATE GROUP-CONTAINING COMPOUNDS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2021-01-14 | — | — | WO | disclosed |
| WO-2021004978-A1 | METHOD FOR PRODUCING ISOCYANURATES FROM URETDIONES | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2021-01-14 | — | — | WO | disclosed |
| WO-2020014971-A1 | IONICALLY HYDROPHILIZED POLYISOCYANATES WITH IMPROVED DRYING | COVESTRO DEUTSCHLAND AG (DE) | 2020-01-23 | — | — | WO | disclosed |
| EP-1989194-B1 | CYCLIC SULFONES USEFUL AS BACE INHIBITORS | NOVARTIS AG (CH) | 2010-08-25 | — | — | EP | disclosed |
| US-20090099207-A1 | Cyclic sulfones useful as BACE inhibitors | RUEEGER HEINRICH | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099207-A1 | Cyclic sulfones useful as BACE inhibitors | BACE1, BACE2, APP | MIF 676/4885HDAC4 2540/4885HDAC2 1215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.