Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2901310 | 0.90 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2901314 | 0.90 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2904317 | 0.90 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2907400 | 0.89 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2901763 | 0.84 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL13239427 | 0.80 | HSD11B1 (0.80) | HSD11B1 | |
| SCHEMBL14107056 | 0.76 | HSD11B1 (0.77) | HSD11B1 | |
| SCHEMBL2901600 | 0.76 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL13239444 | 0.76 | HSD11B1 (0.72) | HSD11B1 | |
| SCHEMBL2902534 | 0.76 | HSD11B1 (1.00) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735275-B1 | ARYL SULFONES AND USES RELATED THERETO | AMGEN INC (US) | 2010-08-18 | — | — | EP | claimed |