Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 1.00 |
| ▸ | PPARG | P37231 | 11/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30390283 | 1.00 | RXRA (1.00) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL17119516 | 1.00 | RXRA (1.00) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL19542342 | 0.90 | RXRA (0.81) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL12181845 | 0.89 | RXRA (0.80) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL30389970 | 0.89 | RXRA (0.80) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL29068228 | 0.86 | RXRA (0.82) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL29068226 | 0.86 | RXRA (0.82) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL30913423 | 0.86 | RXRA (0.76) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL21375994 | 0.85 | RXRA (0.74) | RXRAPPARGCYP1A2MAPTMAPK1 | |
| SCHEMBL12182063 | 0.84 | RXRA (0.79) | RXRAPPARGCYP1A2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472034-A | Indene compound, pharmaceutical composition thereof and therapeutic application thereof | 藤济(厦门)生物医药科技有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-116472034-A | Indene compound, pharmaceutical composition thereof and therapeutic application thereof | 藤济(厦门)生物医药科技有限公司 | 2023-07-21 | — | — | CN | disclosed |