Benzenesulfonamide

Benzenesulfonamide

SCHEMBL29068266

NS(=O)(=O)c1ccccc1.O=S(=O)(NF)c1ccccc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 14/20 0.67
CA2 P00918 14/20 0.67
CA9 Q16790 9/20 0.67
CA12 O43570 8/20 0.67
CA3 P07451 1/20 0.67
CA4 P22748 1/20 0.67
CA6 P23280 1/20 0.67
CA5A P35218 1/20 0.67
CA7 P43166 1/20 0.67
PLA2G7 Q13093 1/20 0.67
CA13 Q8N1Q1 1/20 0.67
CA14 Q9ULX7 1/20 0.67
CA5B Q9Y2D0 1/20 0.67
ALDH1A1 P00352 2/20 0.53
HSD17B10 Q99714 2/20 0.50
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48
MMP13 P45452 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzenesulfonamide SCHEMBL29251509 0.98 CA1 (0.64) CA1CA2CA9CA12CA3
Benzenesulfonamide SCHEMBL28328143 0.94 CA1 (0.59) CA1CA2CA9CA12CA3
SCHEMBL28475473 0.89 CA2 (0.55) CA1CA2CA9CA12CA3
SCHEMBL56650 0.89 CA1 (0.58) CA1CA2CA9CA12CA3
Hydrochloric Acid SCHEMBL21326160 0.87 CA1 (0.56) CA1CA2ALDH1A1MMP1MMP2
Benzenesulfonamide SCHEMBL1332409 0.82 CA2 (1.00) CA1CA2CA9CA12CA3
Benzenesulfonamide SCHEMBL729 0.82 CA2 (1.00) CA1CA2CA9CA12CA3
SCHEMBL19479299 0.82 CA2 (1.00) CA1CA2CA9CA12CA3
Benzenesulfonamide SCHEMBL29825137 0.82 CA2 (1.00) CA1CA2CA9CA12CA3
Benzenesulfonamide SCHEMBL6868390 0.82 CA2 (1.00) CA1CA2CA9CA12CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116554170-A Preparation method of 4-fluoro-7-azaindole 上海大学 2023-08-08 CN claimed
CN-116554170-A Preparation method of 4-fluoro-7-azaindole 上海大学 2023-08-08 CN disclosed