Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23762932 | 0.84 | CTSK (0.43) | CTSKCA1CA2BTKCCR1 | |
| SCHEMBL18838439 | 0.82 | CTSK (0.38) | CTSKCA1CA2BTKHSD11B1 | |
| SCHEMBL18838482 | 0.82 | CTSK (0.38) | CTSKCA1CA2BTKHSD11B1 | |
| SCHEMBL23931093 | 0.82 | CTSK (0.41) | CTSKCA1CA2BTKHSD11B1 | |
| SCHEMBL23931095 | 0.82 | CTSK (0.41) | CTSKCA1CA2BTKHSD11B1 | |
| SCHEMBL18838440 | 0.81 | CTSK (0.43) | CTSKCA1CA2BTKHSD11B1 | |
| SCHEMBL18838483 | 0.81 | CTSK (0.43) | CTSKCA1CA2BTKHSD11B1 | |
| SCHEMBL23852747 | 0.81 | CA1 (0.40) | CTSKCA1CA2BTKCCR1 | |
| SCHEMBL12492955 | 0.80 | CTSK (0.39) | CTSKCA1CA2BTKCCR1 | |
| SCHEMBL26627091 | 0.80 | PDE4B (0.46) | CYP2C9KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745277-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-09-12 | — | — | CN | disclosed |