Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056537 | 0.84 | CHRNA7 (0.49) | CHRNA7CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL26105561 | 0.82 | CHRNA7 (0.50) | CHRNA7CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27301151 | 0.77 | CHRNA7 (0.51) | CHRNA7CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27499699 | 0.75 | CHRNA7 (0.56) | CHRNA7CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14720174 | 0.72 | MEN1 (0.63) | CHRNA7MEN1KMT2AGAAHTR3E | |
| SCHEMBL11592049 | 0.72 | MEN1 (0.63) | CHRNA7MEN1KMT2AGAAHTR3E | |
| SCHEMBL60478 | 0.72 | MEN1 (0.63) | CHRNA7MEN1KMT2AGAAHTR3E | |
| SCHEMBL31139240 | 0.72 | MEN1 (0.63) | CHRNA7MEN1KMT2AGAAHTR3E | |
| SCHEMBL29068614 | 0.71 | CHRNA7 (0.52) | CHRNA7CHRM3MEN1KMT2AGAA | |
| Ammonia Solution, Strong SCHEMBL597060 | 0.71 | MEN1 (0.61) | CHRNA7MEN1KMT2AGAAHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745292-A | Substituted pyridotriazine compounds and uses thereof | 吉利德科学公司 | 2023-09-12 | — | — | CN | disclosed |