Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26105561 | 0.95 | CHRNA7 (0.50) | CHRNA7CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL11056537 | 0.93 | CHRNA7 (0.49) | CHRNA7CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27499699 | 0.87 | CHRNA7 (0.56) | CHRNA7CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL11203722 | 0.78 | ALDH1A1 (0.54) | MEN1KMT2AGAAKDM4ENPC1 | |
| SCHEMBL29068615 | 0.77 | CHRNA7 (0.43) | CHRNA7CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7266561 | 0.76 | LMNA (0.54) | CHRNA7LMNANPC1HPGDRAB9A | |
| SCHEMBL16759127 | 0.76 | CHRNA7 (0.55) | CHRNA7CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL383987 | 0.76 | ELANE (0.48) | CHRNA7CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL28789391 | 0.76 | ELANE (0.48) | CHRNA7CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6825919 | 0.75 | GAA (0.54) | CHRNA7CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1037101-C | 4-substituted 1,2,4-triazole derivatives | MERCK SHARP & DOHME (GB) | 1998-01-21 | — | — | CN | disclosed |
| CN-1089262-A | 1,2 of 4-replacement, the 4-triazole derivative | MERCK SHARP & DOHME (GB) | 1994-07-13 | — | — | CN | disclosed |