SCHEMBL29068688

SCHEMBL29068688

Oc1c(F)c(I)cc(C(F)(F)F)c1F

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.34
KIF11 P52732 1/20 0.33
TTR P02766 1/20 0.32
CES2 O00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31302117 0.82 NOTUM (0.33) KIF11
SCHEMBL17378832 0.78 CHEK1 (0.32) KIF11
SCHEMBL26523664 0.74 KIF11 (0.33) KIF11
SCHEMBL29490992 0.74 KIF11 (0.33) KIF11
SCHEMBL2957907 0.70 CFTR (0.42) CFTRCES2
SCHEMBL17468322 0.70 CFTR (0.31) CFTR
SCHEMBL30206853 0.70 TTR (0.37) CFTRKIF11TTR
SCHEMBL813690 0.70 TTR (0.37) CFTRKIF11TTR
SCHEMBL17378834 0.70 KIF11 (0.37) CFTRKIF11CES2
SCHEMBL319598 0.70 KIF11 (0.41) CFTRKIF11CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116744918-A HSD17B13 inhibitors and uses thereof FL2022-001公司 2023-09-12 CN disclosed