SCHEMBL29070145

SCHEMBL29070145

COc1ccc2c(F)ccc(CCNC(C)=O)c2c1.O=S(=O)(O)c1cccc2c(S(=O)(=O)O)cccc12

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 17/20 0.59
MTNR1B P49286 13/20 0.59
HTR2C P28335 2/20 0.59
HTR2B P41595 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29032167 0.87 MTNR1A (0.64) MTNR1AMTNR1BHTR2CHTR2B
SCHEMBL29070139 0.87 MTNR1A (0.57) MTNR1AMTNR1BHTR2CHTR2B
Oxalic Acid SCHEMBL29070135 0.84 MTNR1A (0.60) MTNR1AMTNR1BHTR2CHTR2B
Urea SCHEMBL29070131 0.84 MTNR1A (0.60) MTNR1AMTNR1BHTR2CHTR2B
Phosphoric Acid SCHEMBL29070121 0.83 MTNR1A (0.59) MTNR1AMTNR1BHTR2CHTR2B
Fumaric Acid SCHEMBL29070144 0.81 MTNR1A (0.57) MTNR1AMTNR1BHTR2CHTR2B
SCHEMBL30449792 0.80 MTNR1A (0.54) MTNR1AMTNR1BHTR2CHTR2B
Aminobenzoic Acid SCHEMBL29070132 0.77 MTNR1A (0.52) MTNR1AMTNR1BHTR2CHTR2B
Agomelatine SCHEMBL16581356 0.77 MTNR1A (0.93) MTNR1AMTNR1BHTR2CHTR2B
Agomelatine SCHEMBL15821818 0.77 MTNR1A (0.93) MTNR1AMTNR1BHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478059-A Crystal form, eutectic crystal form and eutectic crystal form of dicyclic derivative regulator and preparation method thereof 上海翰森生物医药科技有限公司 2023-07-25 CN claimed
CN-116478059-A Crystal form, eutectic crystal form and eutectic crystal form of dicyclic derivative regulator and preparation method thereof 上海翰森生物医药科技有限公司 2023-07-25 CN disclosed