SCHEMBL29070682

SCHEMBL29070682

O=c1c2c3ccc(Br)cc3c(=O)c=2c2ccc(Br)cc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.46
TLR9 Q9NR96 1/20 0.46
PIM1 P11309 3/20 0.43
CHEK1 O14757 2/20 0.43
FLT3 P36888 2/20 0.43
METAP2 P50579 1/20 0.43
AURKA O14965 1/20 0.43
DAPK3 O43293 1/20 0.43
JAK2 O60674 1/20 0.43
PRKD3 O94806 1/20 0.43
MAP4K4 O95819 1/20 0.43
PAK4 O96013 1/20 0.43
ABL1 P00519 1/20 0.43
NTRK1 P04629 1/20 0.43
CSF1R P07333 1/20 0.43
RET P07949 1/20 0.43
MET P08581 1/20 0.43
PDGFRB P09619 1/20 0.43
FGFR1 P11362 1/20 0.43
PDGFRA P16234 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6195766 0.82 HSP90AA1 (0.48) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL29772248 0.80 HSP90AA1 (0.46) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL14873561 0.80 HSP90AA1 (0.46) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL12148722 0.80 HSP90AA1 (0.46) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL1685385 0.80 HSP90AA1 (0.46) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL12148734 0.78 BCL2 (0.47) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL19164101 0.78 MEN1 (0.46) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL19164169 0.76 MEN1 (0.44) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL22599843 0.76 MEN1 (0.44) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL19164173 0.75 MEN1 (0.47) HSP90AA1TLR9PIM1CHEK1FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113149864-B Synthesis and application of thermal activity delay fluorescent material based on indeno [2,1-a ] indene condensed ring unit 安徽秀朗新材料科技有限公司 2023-09-12 CN claimed
CN-113149864-B Synthesis and application of thermal activity delay fluorescent material based on indeno [2,1-a ] indene condensed ring unit 安徽秀朗新材料科技有限公司 2023-09-12 CN disclosed