Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | GAA | P10253 | 8/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | BPTF | Q12830 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451294 | 0.81 | ALDH1A1 (0.60) | ALDH1A1GAAHSD17B10KDM4EMEN1 | |
| SCHEMBL5451299 | 0.81 | ALDH1A1 (0.60) | ALDH1A1GAAHSD17B10KDM4EMEN1 | |
| SCHEMBL5629040 | 0.81 | MAPT (0.73) | ALDH1A1GAAHSD17B10KDM4EMEN1 | |
| SCHEMBL3498811 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAAHSD17B10KDM4EMEN1 | |
| SCHEMBL1207493 | 0.77 | ALDH1A1 (0.49) | ALDH1A1GAAHSD17B10KDM4EMEN1 | |
| SCHEMBL3496757 | 0.77 | ALDH1A1 (0.61) | ALDH1A1GAAHSD17B10KDM4EMEN1 | |
| SCHEMBL6376110 | 0.75 | MAPT (0.53) | ALDH1A1GAAHSD17B10KDM4EMEN1 | |
| SCHEMBL24091680 | 0.75 | ALDH1A1 (0.86) | ALDH1A1GAAHSD17B10KDM4EMEN1 | |
| SCHEMBL18135595 | 0.75 | MAPT (0.74) | ALDH1A1GAAHSD17B10KDM4EMEN1 | |
| SCHEMBL1208527 | 0.74 | BPTF (0.50) | ALDH1A1GAAHSD17B10KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490505-A | MNK inhibitors | 和博医药有限公司 | 2023-07-25 | — | — | CN | disclosed |
| EP-4200296-A1 | MNK INHIBITORS | Hepagene Therapeutics (HK) Limited (HK) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022038563-A1 | MNK INHIBITORS | Hepagene Therapeutics (HK) Limited (CN) | 2022-02-24 | — | — | WO | disclosed |