Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30513272 | 1.00 | POLB (0.41) | POLBMKNK1KITCNR1CNR2 | |
| SCHEMBL31006861 | 0.84 | POLB (0.39) | POLBMKNK1GPR119UCHL1MEN1 | |
| SCHEMBL31584973 | 0.82 | KIT (0.39) | MKNK1KITCNR1CNR2GPR119 | |
| SCHEMBL29736736 | 0.81 | POLB (0.43) | POLBMKNK1GPR119UCHL1MEN1 | |
| SCHEMBL1013846 | 0.81 | POLB (0.48) | POLBMKNK1GPR119MEN1KMT2A | |
| SCHEMBL15553247 | 0.81 | POLB (0.43) | POLBMKNK1GPR119UCHL1MEN1 | |
| SCHEMBL1497077 | 0.80 | MKNK1 (0.48) | POLBMKNK1ESR2 | |
| SCHEMBL18786791 | 0.79 | POLB (0.39) | POLBKITCNR1CNR2GPR119 | |
| SCHEMBL31600885 | 0.79 | GPR119 (0.36) | POLBMKNK1GPR119UCHL1 | |
| SCHEMBL31514682 | 0.79 | POLB (0.37) | POLBGPR119UCHL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106482-A1 | COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) | 2025-05-22 | — | — | WO | disclosed |
| CN-116490505-A | MNK inhibitors | 和博医药有限公司 | 2023-07-25 | — | — | CN | disclosed |