Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686425 | 0.85 | MEN1 (0.47) | CYP19A1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL1554959 | 0.78 | TDP1 (0.52) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11413066 | 0.77 | NPC1 (0.52) | NPC1RAB9AABCB1SMN1; SMN2HTR1A | |
| SCHEMBL6614268 | 0.77 | NPC1 (0.52) | NPC1RAB9AABCB1SMN1; SMN2HTR1A | |
| SCHEMBL11125245 | 0.77 | ALDH1A1 (0.47) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL16959987 | 0.76 | NPC1 (0.46) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29070968 | 0.76 | NPC1 (0.51) | NPC1RAB9AABCB1SMN1; SMN2HTR1A | |
| SCHEMBL919788 | 0.76 | NPC1 (0.51) | NPC1RAB9AABCB1HTR1AADRA1D | |
| SCHEMBL11355167 | 0.76 | NPC1 (0.42) | CYP19A1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11413069 | 0.75 | NPC1 (0.49) | NPC1RAB9AABCB1SMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332948-A | Nitrogen-containing tetracyclic compound, preparation method and medicinal application thereof | 翰森生物有限责任公司 | 2023-06-27 | — | — | CN | disclosed |