Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779505 | 0.98 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1KMT2AGAA | |
| SCHEMBL26914635 | 0.98 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1KMT2AGAA | |
| SCHEMBL18797 | 0.98 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1KMT2AGAA | |
| SCHEMBL9131994 | 0.98 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1KMT2AGAA | |
| Cyclohexane SCHEMBL28249403 | 0.98 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1KMT2AGAA | |
| SCHEMBL25311355 | 0.98 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1KMT2AGAA | |
| SCHEMBL9134377 | 0.98 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1KMT2AGAA | |
| SCHEMBL1439129 | 0.96 | TDP1 (0.48) | TDP1L3MBTL1ALDH1A1KMT2AGAA | |
| Acetic Acid SCHEMBL17748838 | 0.92 | TDP1 (0.47) | TDP1L3MBTL1ALDH1A1KMT2AGAA | |
| SCHEMBL1881523 | 0.92 | ALDH1A1 (0.46) | TDP1L3MBTL1ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761635-A | BCL-XL inhibitor antibody drug conjugates and methods of use thereof | 诺华股份有限公司 | 2023-09-15 | — | — | CN | disclosed |