Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.69 |
| ▸ | MET | P08581 | 9/20 | 0.59 |
| ▸ | CSF1R | P07333 | 5/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | YES1 | P07947 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | HCK | P08631 | 1/20 | 0.46 |
| ▸ | FGR | P09769 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | CSK | P41240 | 1/20 | 0.46 |
| ▸ | BLK | P51451 | 1/20 | 0.46 |
| ▸ | BMX | P51813 | 1/20 | 0.46 |
| ▸ | SRMS | Q9H3Y6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29071128 | 0.88 | MET (0.62) | MAPK1METCSF1R | |
| SCHEMBL29071331 | 0.87 | MET (0.61) | MAPK1METCSF1RABL1LCK | |
| SCHEMBL29071405 | 0.85 | MET (0.59) | MAPK1METCSF1R | |
| SCHEMBL29071359 | 0.85 | CSF1R (0.65) | MAPK1CSF1RABL1LCKFYN | |
| SCHEMBL16679782 | 0.82 | MAPK1 (1.00) | MAPK1MET | |
| SCHEMBL29071150 | 0.81 | MET (0.60) | MAPK1METCSF1RABL1LCK | |
| SCHEMBL29071369 | 0.80 | MAPK1 (0.56) | MAPK1METCSF1RABL1LCK | |
| SCHEMBL29071182 | 0.79 | MAPK1 (0.54) | MAPK1METCSF1RABL1LCK | |
| SCHEMBL29071388 | 0.77 | MAPK1 (0.52) | MAPK1METCSF1R | |
| SCHEMBL29071394 | 0.76 | CSF1R (0.57) | MAPK1METCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730978-A | Compound containing heteroaromatic ring alkynyl, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-09-12 | — | — | CN | disclosed |