Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 14/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 13/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 13/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 8/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24461526 | 0.87 | SMARCA2 (0.53) | PBRM1SMARCA2SMARCA4SMN1; SMN2 | |
| SCHEMBL29619399 | 0.87 | SMARCA2 (0.53) | PBRM1SMARCA2SMARCA4SMN1; SMN2 | |
| SCHEMBL31505518 | 0.85 | BTK (0.42) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL30552632 | 0.84 | SMARCA2 (0.42) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL24461569 | 0.84 | SMARCA2 (0.42) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL30552600 | 0.84 | SMARCA2 (0.42) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL24461303 | 0.83 | SMARCA2 (0.45) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL24461291 | 0.82 | IKBKB (0.39) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL31505612 | 0.82 | IKBKB (0.39) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL31505590 | 0.76 | PBRM1 (0.34) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744929-A | Compounds and uses thereof | 福霍恩治疗公司 | 2023-09-12 | — | — | CN | disclosed |