Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 17/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 16/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 16/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 10/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31505542 | 0.84 | HTR3A (0.33) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL31505642 | 0.84 | PBRM1 (0.36) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL31505570 | 0.83 | HTR3A (0.36) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL24461291 | 0.82 | IKBKB (0.39) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL31505612 | 0.82 | IKBKB (0.39) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL31505553 | 0.81 | SMARCA2 (0.31) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL31505658 | 0.80 | SMARCA2 (0.31) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL30552600 | 0.80 | SMARCA2 (0.42) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL24461569 | 0.80 | SMARCA2 (0.42) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 | |
| SCHEMBL30552632 | 0.80 | SMARCA2 (0.42) | PBRM1SMARCA2SMARCA4NR1I2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101944-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A | Plexium, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |