⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720545 | 0.86 | L3MBTL1 (0.35) | — | |
| SCHEMBL19290148 | 0.85 | CYP1A2 (0.50) | — | |
| SCHEMBL132919 | 0.85 | CYP1A2 (0.39) | — | |
| SCHEMBL6130376 | 0.85 | CYP1A2 (0.39) | — | |
| SCHEMBL6130374 | 0.85 | CYP1A2 (0.39) | — | |
| SCHEMBL6130378 | 0.85 | CYP1A2 (0.39) | — | |
| SCHEMBL6130373 | 0.85 | CYP1A2 (0.39) | — | |
| SCHEMBL10341950 | 0.83 | CYP1A2 (0.40) | — | |
| SCHEMBL6130370 | 0.83 | CYP1A2 (0.40) | — | |
| SCHEMBL598587 | 0.83 | CYP1A2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144871-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | ABBVIE INC. | 2023-05-11 | — | — | US | disclosed |
| CN-115895083-A | Foam core metal composite plate and preparation method thereof | 江苏卡普丹建筑科技有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2023001069-A1 | MACROCYCLIC AMIDE COMPOUNDS AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-26 | — | — | WO | disclosed |
| EP-2820027-B1 | METATHESIS CATALYSTS CONTAINING ONIUM GROUPS | APEIRON SYNTHESIS SA (PL) | 2018-06-06 | — | — | EP | disclosed |
| US-9718828-B2 | BTK Inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-08-01 | — | — | US | disclosed |
| US-20150148473-A1 | APAO-based hot melt adhesives | RexTac LLC. | 2015-05-28 | — | — | US | disclosed |
| EP-1537099-B1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-11 | — | — | EP | disclosed |
| US-7671049-B2 | Pyrrole based inhibitors of glycogen synthase kinase 3 | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2010-03-02 | — | — | US | disclosed |
| US-20070244109-A1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2007-10-18 | — | — | US | disclosed |
| US-7250443-B2 | Pyrrole based inhibitors of glycogen synthase kinase 3 | CHIRON CORPORATION (US) | 2007-07-31 | — | — | US | disclosed |
| US-4401824-A | Benzopyran compounds, derivatives of prostaglandins | THE UPJOHN COMPANY (US) | 1983-08-30 | — | — | US | disclosed |
| EP-0086611-A1 | 9-Substituted carbacyclin analogues | THE UPJOHN COMPANY (US) | 1983-08-24 | — | — | EP | disclosed |
| EP-0068871-A2 | Prostaglandin analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-01-05 | — | — | EP | disclosed |
| US-4349689-A | Methano carbacyclin analogs | THE UPJOHN COMPANY (US) | 1982-09-14 | — | — | US | disclosed |
| US-4306075-A | Composition and process | THE UPJOHN COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
| US-4306076-A | Inter-phenylene CBA compounds | THE UPJOHN COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
| US-4278688-A | Prostaglandin analogues | ONO PHARMACEUTICAL CO. (JP) | 1981-07-14 | — | — | US | disclosed |
| US-4234597-A | 6,9-Nitrilo(imino)-prostaglandin analogues | ONO PHARMACEUTICAL CO. LTD. (JP) | 1980-11-18 | — | — | US | disclosed |
| US-4232009-A | PROSTAGLANDINS, CYCLODEXTRIN CLATHRATES, HYPOTENSIVES | ONO PHARMACEUTICAL CO. LTD. (JP) | 1980-11-04 | — | — | US | disclosed |
| US-4215142-A | Prostaglandin analogues | ONO PHARMACEUTICAL CO. LTD. (JP) | 1980-07-29 | — | — | US | disclosed |