SCHEMBL29072113

SCHEMBL29072113

CC(C)(C)N(C(=O)CCCNC(=O)OCc1ccccc1)C(CCCCNC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 8/20 0.64
HTT P42858 1/20 0.55
MAPT P10636 1/20 0.50
TPSAB1 Q15661 2/20 0.49
TPSD1 Q9BZJ3 2/20 0.49
TPSG1 Q9NRR2 2/20 0.49
DPP8 Q6V1X1 1/20 0.49
DPP7 Q9UHL4 1/20 0.49
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
SLC1A3 P43003 1/20 0.47
SLC1A1 P43005 1/20 0.47
TGM2 P21980 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29072092 0.86 FOLH1 (0.77) FOLH1HTTDPP8DPP7MMP2
SCHEMBL29072123 0.82 CPB1 (0.54) FOLH1HTTMMP2MMP9
SCHEMBL14561119 0.79 FOLH1 (0.70) FOLH1HTTMAPTTPSAB1TPSD1
SCHEMBL17646347 0.79 FOLH1 (0.56) FOLH1HTTMAPTTPSAB1TPSD1
SCHEMBL17646421 0.79 FOLH1 (0.56) FOLH1HTTMAPTTPSAB1TPSD1
SCHEMBL22804057 0.78 FOLH1 (0.60) FOLH1HTTMAPTTPSAB1TPSD1
SCHEMBL15844493 0.78 FOLH1 (0.68) FOLH1HTTDPP8DPP7MMP2
SCHEMBL20510519 0.78 FOLH1 (0.68) FOLH1HTTDPP8DPP7MMP2
SCHEMBL8211666 0.78 FOLH1 (0.68) FOLH1HTTDPP8DPP7MMP2
SCHEMBL22737146 0.78 FOLH1 (1.00) FOLH1HTTDPP8DPP7MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116744944-A Low-immunogenicity biotherapeutic medicine 奥斯普瑞生物制药有限公司 2023-09-12 CN disclosed