Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.60 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29072109 | 1.00 | KLK7 (0.60) | KLK7KLK5MAPTFOLH1ABCB1 | |
| SCHEMBL29727709 | 0.96 | KLK7 (0.57) | KLK7KLK5MAPTFOLH1ABCB1 | |
| SCHEMBL20450593 | 0.94 | FOLH1 (0.60) | KLK7KLK5MAPTFOLH1ABCB1 | |
| SCHEMBL20450594 | 0.94 | FOLH1 (0.60) | KLK7KLK5MAPTFOLH1ABCB1 | |
| SCHEMBL20450591 | 0.93 | MAPT (0.58) | KLK7KLK5MAPTFOLH1ABCB1 | |
| SCHEMBL20450589 | 0.93 | MAPT (0.58) | KLK7KLK5MAPTFOLH1ABCB1 | |
| SCHEMBL22972745 | 0.91 | KLK7 (0.59) | KLK7KLK5MAPTFOLH1ABCB1 | |
| SCHEMBL28902004 | 0.91 | KLK7 (0.59) | KLK7KLK5MAPTFOLH1ABCB1 | |
| SCHEMBL28902002 | 0.91 | KLK7 (0.59) | KLK7KLK5MAPTFOLH1ABCB1 | |
| SCHEMBL17309872 | 0.90 | MAPT (0.68) | KLK7KLK5MAPTFOLH1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744944-A | Low-immunogenicity biotherapeutic medicine | 奥斯普瑞生物制药有限公司 | 2023-09-12 | — | — | CN | disclosed |