Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22827746 | 0.86 | RAB9A (0.52) | RAB9ASMN1; SMN2MAPK1LMNAKCNMA1 | |
| Hydrochloric Acid SCHEMBL29489971 | 0.85 | RAB9A (0.51) | RAB9ASMN1; SMN2MAPK1LMNAKCNMA1 | |
| Hydrochloric Acid SCHEMBL20577413 | 0.85 | RAB9A (0.51) | RAB9ASMN1; SMN2MAPK1LMNAKCNMA1 | |
| Hydrochloric Acid SCHEMBL29365947 | 0.85 | RAB9A (0.51) | RAB9ASMN1; SMN2MAPK1LMNAKCNMA1 | |
| SCHEMBL20577393 | 0.81 | RAB9A (0.49) | RAB9ASMN1; SMN2MAPK1LMNAKCNMA1 | |
| SCHEMBL22805168 | 0.77 | RAB9A (0.45) | RAB9ASMN1; SMN2MAPK1LMNAKCNMA1 | |
| SCHEMBL29489965 | 0.77 | RAB9A (0.45) | RAB9ASMN1; SMN2MAPK1LMNAKCNMA1 | |
| SCHEMBL28698173 | 0.76 | MEN1 (0.44) | RAB9ASMN1; SMN2MAPK1LMNAKCNMA1 | |
| SCHEMBL1339948 | 0.76 | EGFR (0.54) | RAB9ASMN1; SMN2MAPK1LMNAKCNMA1 | |
| SCHEMBL20299521 | 0.75 | RAB9A (0.47) | RAB9ASMN1; SMN2MAPK1LMNAKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693518-A | Synthesis and application of EGFR inhibitor | 江南大学 | 2023-09-05 | — | — | CN | disclosed |