Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29072303 | 1.00 | HSD17B10 (0.43) | HSD17B10MMP2ANPEPSMN1; SMN2LMNA | |
| SCHEMBL25369568 | 1.00 | HSD17B10 (0.43) | HSD17B10MMP2ANPEPSMN1; SMN2LMNA | |
| SCHEMBL13962503 | 0.88 | MMP2 (0.56) | HSD17B10MMP2ANPEPSMN1; SMN2LMNA | |
| SCHEMBL26715491 | 0.88 | MMP2 (0.56) | HSD17B10MMP2ANPEPSMN1; SMN2LMNA | |
| SCHEMBL15221383 | 0.88 | MMP2 (0.56) | HSD17B10MMP2ANPEPSMN1; SMN2LMNA | |
| SCHEMBL20705291 | 0.87 | MMP2 (0.51) | HSD17B10MMP2ANPEPSMN1; SMN2CHRM2 | |
| SCHEMBL29071685 | 0.87 | MMP2 (0.51) | HSD17B10MMP2ANPEPSMN1; SMN2CHRM2 | |
| SCHEMBL23038367 | 0.87 | MMP2 (0.51) | HSD17B10MMP2ANPEPSMN1; SMN2CHRM2 | |
| SCHEMBL13836866 | 0.87 | MMP2 (0.51) | HSD17B10MMP2ANPEPSMN1; SMN2CHRM2 | |
| SCHEMBL17859969 | 0.87 | MMP2 (0.51) | HSD17B10MMP2ANPEPSMN1; SMN2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348472-A | Macrocyclic compounds | 旭化成制药株式会社 | 2023-06-27 | — | — | CN | disclosed |