Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29072991 | 0.87 | NPSR1 (0.56) | KDM4EHPGDMAPTPDE4BMEN1 | |
| SCHEMBL16324708 | 0.84 | PDE4D (0.56) | KDM4EHPGDMAPTPDE4BPDE4D | |
| SCHEMBL9051830 | 0.74 | KMT2A (0.43) | KDM4EMAPTMAPK1MEN1KMT2A | |
| SCHEMBL27297862 | 0.73 | PDE4B (0.44) | KDM4EHPGDMAPTMAPK1PDE4B | |
| SCHEMBL17429964 | 0.73 | PDE4A (0.55) | KDM4EHPGDMAPTMAPK1PDE4B | |
| SCHEMBL538328 | 0.72 | MAPT (0.54) | KDM4EHPGDMAPTMAPK1PDE4B | |
| SCHEMBL15875275 | 0.71 | MAPT (0.44) | KDM4EHPGDMAPTMAPK1PDE4B | |
| SCHEMBL15754546 | 0.71 | CYP1A2 (0.47) | KDM4EHPGDMAPTMAPK1PDE4B | |
| SCHEMBL4702010 | 0.71 | MAPT (0.64) | KDM4EHPGDMAPTMAPK1PDE4B | |
| SCHEMBL3693925 | 0.71 | MAPT (0.53) | KDM4EHPGDMAPTMAPK1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999205-B | Pyridine compound containing triazolone amide and imidazolone amide structures and application thereof | 辽宁大学 | 2023-09-15 | — | — | CN | disclosed |