Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29073000 | 0.87 | KDM4E (0.53) | NPSR1ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL16324708 | 0.82 | PDE4D (0.56) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL29072994 | 0.81 | DHODH (0.48) | NPSR1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL30582367 | 0.80 | DHODH (0.48) | NPSR1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL16796453 | 0.79 | ALDH1A1 (0.48) | NPSR1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL29250863 | 0.79 | NPSR1 (0.57) | NPSR1ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL17430272 | 0.75 | NPSR1 (0.56) | NPSR1ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL3698071 | 0.73 | NPSR1 (0.57) | NPSR1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL28817913 | 0.73 | NPSR1 (0.56) | NPSR1ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL12099796 | 0.72 | NPSR1 (0.56) | NPSR1ALDH1A1HPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999205-B | Pyridine compound containing triazolone amide and imidazolone amide structures and application thereof | 辽宁大学 | 2023-09-15 | — | — | CN | disclosed |