Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.59 |
| ▸ | HTR2C | P28335 | 4/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | GPR183 | P32249 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | APLNR | P35414 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29072943 | 0.93 | HTR2A (0.62) | HTR2AHTR2CABCB11CYP1A2ADRB2 | |
| SCHEMBL29072957 | 0.93 | HTR2A (0.62) | HTR2AHTR2CABCB11CYP1A2ADRB2 | |
| SCHEMBL29072938 | 0.93 | HTR2A (0.62) | HTR2AHTR2CABCB11CYP1A2ADRB2 | |
| SCHEMBL23686868 | 0.91 | HTR2A (0.66) | HTR2AHTR2CABCB11CYP1A2ADRB2 | |
| SCHEMBL29072931 | 0.90 | HTR2A (0.60) | HTR2AHTR2CABCB11CYP1A2ADRB2 | |
| SCHEMBL20766015 | 0.86 | HTR2A (0.70) | HTR2AHTR2CABCB11CYP1A2ADRB2 | |
| SCHEMBL20774949 | 0.86 | HTR2A (0.70) | HTR2AHTR2CABCB11CYP1A2ADRB2 | |
| SCHEMBL23686966 | 0.86 | HTR2A (0.70) | HTR2AHTR2CABCB11CYP1A2ADRB2 | |
| SCHEMBL29072941 | 0.86 | HTR2A (0.67) | HTR2AHTR2CABCB11CYP1A2ADRB2 | |
| SCHEMBL29073209 | 0.86 | HTR2A (0.67) | HTR2AHTR2CABCB11CYP1A2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111385-B | 5-HT 2A Receptor inhibitor and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |