Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | HTR2C | P28335 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | PPARD | Q03181 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24601053 | 1.00 | ADORA3 (0.70) | ADORA3ADORA2AADORA1ADORA2BMAPK1 | |
| SCHEMBL29073499 | 1.00 | ADORA3 (0.70) | ADORA3ADORA2AADORA1ADORA2BMAPK1 | |
| SCHEMBL29762223 | 0.95 | ADORA3 (0.63) | ADORA3ADORA2AADORA1ADORA2BMAPK1 | |
| SCHEMBL26628532 | 0.94 | ADORA3 (0.61) | ADORA3ADORA2AADORA1ADORA2BMAPK1 | |
| SCHEMBL30850628 | 0.94 | ADORA3 (0.61) | ADORA3ADORA2AADORA1ADORA2BMAPK1 | |
| SCHEMBL29073631 | 0.94 | ADORA3 (0.63) | ADORA3ADORA2AADORA1ADORA2BMAPK1 | |
| SCHEMBL29762354 | 0.94 | ADORA3 (0.63) | ADORA3ADORA2AADORA1ADORA2BMAPK1 | |
| SCHEMBL24600664 | 0.94 | ADORA3 (0.63) | ADORA3ADORA2AADORA1ADORA2BMAPK1 | |
| SCHEMBL29073633 | 0.94 | ADORA3 (0.63) | ADORA3ADORA2AADORA1ADORA2BMAPK1 | |
| SCHEMBL26628474 | 0.94 | ADORA3 (0.63) | ADORA3ADORA2AADORA1ADORA2BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783196-A | A3 adenosine receptor agonists, methods of making and uses thereof | 浙江春禾医药科技有限公司 | 2023-09-19 | — | — | CN | claimed |