Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | MELK | Q14680 | 2/20 | 0.34 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.34 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | MYLK | Q15746 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909795 | 0.87 | NR1H4 (0.39) | NR1H4KDM4EDHODHGAAKMT2A | |
| SCHEMBL2915054 | 0.86 | NR1H4 (0.40) | NR1H4KDM4EDHODHALDH1A1KMT2A | |
| SCHEMBL2913600 | 0.86 | NR1H4 (0.40) | NR1H4KDM4EDHODHALDH1A1KMT2A | |
| SCHEMBL2913384 | 0.86 | NR1H4 (0.40) | ACHENR1H4KDM4EDHODHGAA | |
| SCHEMBL2917122 | 0.84 | MAPT (0.42) | NR1H4DHODHALDH1A1KMT2AITGA4 | |
| SCHEMBL2907801 | 0.84 | TLK2 (0.42) | ACHENR1H4 | |
| SCHEMBL2907136 | 0.83 | NR1H4 (0.38) | ACHENR1H4KDM4EDHODHKMT2A | |
| SCHEMBL2907824 | 0.83 | MAPT (0.39) | NR1H4KDM4EALDH1A1GAAITGA4 | |
| SCHEMBL1530474 | 0.82 | AURKB (0.42) | ACHENR1H4FLT3MELKCAMK2G | |
| SCHEMBL2910598 | 0.82 | NR1H4 (0.56) | NR1H4KDM4EMAPTPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |