Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23361057 | 1.00 | GPR119 (0.45) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL24510956 | 1.00 | GPR119 (0.45) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL29693973 | 1.00 | GPR119 (0.45) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL24509732 | 1.00 | GPR119 (0.45) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL24510347 | 1.00 | GPR119 (0.45) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL23361204 | 0.89 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBJAK2 | |
| SCHEMBL31213542 | 0.89 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBJAK2 | |
| SCHEMBL19272699 | 0.87 | NR1H2 (0.49) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL2355843 | 0.87 | NR1H2 (0.49) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL15012086 | 0.87 | NR1H2 (0.49) | GPR119KDM4EMAPTTHRBNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003673-B | Dihydropyrimidine compound, preparation method and application thereof | 上海维申医药有限公司 | 2023-08-11 | — | — | CN | disclosed |