Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 3/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | POLA1 | P09884 | 1/20 | 0.58 |
| ▸ | POLG | P54098 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5942289 | 0.95 | FAP (0.62) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2911461 | 0.88 | FAP (0.56) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2905475 | 0.84 | FAP (0.62) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2912754 | 0.81 | FAP (0.63) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL5942564 | 0.80 | FAP (0.64) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2913606 | 0.80 | FAP (0.60) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2911836 | 0.80 | FAP (0.69) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2911598 | 0.78 | CYP3A4 (0.55) | SLC22A6CYP3A4ADORA2AADORA1METTL3 | |
| SCHEMBL4271570 | 0.77 | FAP (0.69) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL5942300 | 0.76 | FAP (0.59) | FAPSLC22A6ABCB11POLA1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | disclosed |