Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 6/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 4/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29077857 | 0.88 | MAP1LC3B (0.36) | FURINMAP1LC3BFAPSIRT2SIRT1 | |
| SCHEMBL15699736 | 0.85 | FURIN (0.40) | FURINMAP1LC3BSIRT1SMN1; SMN2KLKB1 | |
| SCHEMBL19681567 | 0.84 | FURIN (0.39) | FURINMAP1LC3BFAPSMN1; SMN2KLKB1 | |
| SCHEMBL23880545 | 0.84 | TLR2 (0.39) | FURINMAP1LC3BFAP | |
| SCHEMBL31035902 | 0.84 | TLR2 (0.39) | FURINMAP1LC3BFAP | |
| SCHEMBL30509100 | 0.84 | TLR2 (0.39) | FURINMAP1LC3BFAP | |
| SCHEMBL25787504 | 0.83 | FURIN (0.40) | FURINMAP1LC3BSIRT1SMN1; SMN2KLKB1 | |
| SCHEMBL84146 | 0.83 | TLR2 (0.39) | FURINMAP1LC3BFAP | |
| SCHEMBL22138596 | 0.82 | FURIN (0.39) | FURINSMN1; SMN2KLKB1 | |
| SCHEMBL20705515 | 0.82 | FURIN (0.39) | FURINSMN1; SMN2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118085100-A | Camptothecin analogues conjugated to glutamine residues in proteins and uses thereof | 瑞泽恩制药公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-116390771-A | Camptothecin analogues conjugated to glutamine residues in proteins and uses thereof | 瑞泽恩制药公司 | 2023-07-04 | — | — | CN | disclosed |